How many calories to burn fat on a threadmill?

Can you answer Trina M’s question about Weight Loss?:

I’m 25, good health, but I do have asthma. Not very bad. I weigh 202 pounds. Lean not fat. I do have a little fat but I’m mostly lean. I want to get down to 145. How many calories do I burn? Why is it good for your heart to beat fast or get to a certain level? I really need a little schooling on this. Thanks. Oh, after I eat, how long do I wait to exercise and hoe long do I walk on the threadmill?

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